In terms of strain identity, out of a previously defined panel of 18 possible Tau strains deriving from diverse source materials (recombinant Tau fibrils, cell lines, human brain material from different Tauopathies, mouse brain material), the signature morphology from TgTauP301L mice most closely resembled a strain isolate called DS6 [35]. The gene discussed is MAPT; the disease is tauopathy.