ABCB1 and neoplasm: This suggested that compared with free gefitinib, the added CQ and mAb MDR1 acted as potential tumor cell inhibitors which played a role in increasing the cells’ sensitivity to the apoptosis signal, but for the degradation of mAb MDR1 by the enzyme and the difficult uptake of CQ by passive diffusion, it was difficult to significantly improve cell apoptosis in the free state.