As shown in Fig. 3c, treatment with GOLPH3L-shRNA plus cisplatin resulted in a significantly reduction, but overexpression GOLPH3L resulted in a significantly increase in tumor growth compared with that in the control group (Tumor weight: Vector vs GOLPH3L = 373.4 ± 6.1 g vs 763 ± 11.2 g; control vs GOLPH3L-shRNA = 683.4 ± 9.2 g VS 58.7 ± 2.1 g, P < 0.01). This evidence concerns the gene GOLPH3L and neoplasm.