FOXM1 and neoplasm: The results showed that overexpression of miR-216b could significantly inhibit cell proliferation in HeLa cells (Fig. 2) and decrease the ratio of cells in S period (Additional file 1: Figure S1), but its effect on tumor invasion and migration was not obvious (data not shown), indicating that miR-216b may regulate FOXM1-related cell proliferation factors, but not FOXM1-related metastasis factors, and there may be other microRNA-FOXM1 pathways involved in FOXM1 related cell metastasis.