PROM1 and osteosarcoma: Overexpression of miR-29b-1 reduced the expression of stem cell markers (Oct3/4, Sox2, Nanog, CD133, and N-Myc) and anti-apoptotic markers (Bcl-2 and IAP-2) in 3AB-OS CSCs, suggesting that miR-29b-1 can inhibit stemness properties of 3AB-OS CSCs and sensitize 3AB-OS cells to chemotherapy drugs (DOX, CDDP and etoposide) in osteosarcoma [105].