Nearly 65% of NSCLC samples possessed somatic mutations on A-driver genes, which were mainly focused on EGFR (42.72%, 38/103), KRAS (14.56%, 15/103), PIK3CA (3.88%, 4/103), and FGFR3 (2.91%, 3/103). The gene discussed is EGFR; the disease is non-small cell lung carcinoma.