Altered expression of iASPP in many tumor cells can be post-transcriptionally regulated by various miRNAs such as miRNA-124 [30–33], miRNA-140 [34, 35], miRNA-184 [36] and miRNA-506 [37], which involve in modulating the growth or invasion of these cells by targeting iASPP. This evidence concerns the gene PPP1R13L and neoplasm.