On the other hand, changes related to α3 and α5 mRNA levels found in SQC-L and ADC-L tumors in our study concur with a previous paper describing transcriptional dysregulation for CHRNA3 and CHRNA5 in lung tumor biopsies paired with their corresponding non-tumor specimens from 21 patients with ADC-L [30]. This evidence concerns the gene CHRNA3 and neoplasm.