IDH1 and neoplasm: According to the log-rank analysis, the clinical factors correlated with longer PFS included age ≤40 (P<0.001), KPS ≥70 (P<0.001), total resection of tumor (P=0.034), tumor size <6 cm (P=0.041), Ki-67 <20% (P<0.001), lower tumor grade (P<0.001), 1q/19p co-polysomy (P<0.001), no single polysomy (P=0.001), and IDH1/2 mutation (P=0.007), as shown in Table 4.