Furthermore, an inducible, cisplatinum dose-dependent MEOX2 protein expression pattern was identified in lung adenocarcinoma cells (Supplementary Figure 2B), corresponding to cisplatinum-induced GLI-1 protein expression in the lung adenocarcinoma cell lines A427 and A549 that was markedly reduced by anti-MEOX2 siRNAs (Figure 5B). This evidence concerns the gene MEOX2 and lung adenocarcinoma.