Differential MEOX2/RNA Pol II occupancy throughout the epigenome at gene promoter sequences was likely accompanied by the enrichment of active versus repressive epigenetic histone markers, as determined when we compared the epigenome of solid lung adenocarcinomas (identified in the present work) with the previously reported lung cancer epigenome from the lung cell line A549 obtained from the ENCODE project database (Figure 1B). This evidence concerns the gene MEOX2 and lung cancer.