A statistically significant molecular signature consisting of 78 gene promoters (FDR≤0.2) or 13 gene promoters (FDR≤0.1) was shared by different lung carcinoma patients; these promoters included Sonic Hedgehog-GLI-1 gene promoter sequences, which have not been previously been reported to be under MEOX2 transcriptional influence. Here, GLI1 is linked to lung carcinoma.