PD-L1 IC0, IC1 and IC2/3 expression on TCs in metastatic tumor samples was 63% (n=17/27), 18.5% (n=5/27) and 18.5% (n=5/27), including a representative example for IC0 and IC2/3 PD-L1 expression shown in Figure 3. This evidence concerns the gene CD274 and metastatic neoplasm.