IL10 and cancer: A significant association was found between IL-10 -819T/C polymorphism and overall cancer risk (homozygous: OR = 1.19, 95% CI = 1.00-1.41, P < 0.001; recessive: OR = 1.17, 95% CI = 1.00-1.36, P < 0.001 and allele comparison: OR = 1.08, 95% CI = 1.00-1.18, P < 0.001).