Similar results were found when pre-NACT PC values were correlated with CRS: CRS1 corresponded to a median 20% CCNE1 positivity, while both CRS2 and CRS3 corresponded to a median 30% CCNE1 positivity (Figure 3A bottom, Pearson correlation, r(20)=0.24, p=0.15). The gene discussed is CCNE1; the disease is congenital rubella syndrome.