BC patients with high expression of Eg5 protein had significantly shorter overall survival (P = 0.002) compared with those with low or no Eg5 expression (Figure 3A), and patients with a high Ki67 expression had a poorer overall survival (P < 0.001) than patients with Ki67-low tumors (Figure 3B), patients in TNM stage III had a lower overall survival (P = 0.001) than patients in TNM stageI-II (Figure 3C). The gene discussed is MKI67; the disease is breast cancer.