CXCL8 and primary cutaneous T-cell non-Hodgkin lymphoma: In addition to TNFα, the epidermis in patients with CTCL contains increased levels of NF-κB-dependent pro-inflammatory cytokines IL-1β, IL-8, IL-17, and IL-32 suggesting a role for these cytokines in the pathogenesis of CTCL [18-21].