Our previous study [6] revealed the prognostic value of a combined TMPRSS2-ERG and TERT expression analysis, while the data of other authors [10, 11, 23] and our present study suggested up-regulation of EZH2 and down-regulation of MT1E as the possible biomarkers of poor prognosis in PCa. Here, TMPRSS2 is linked to posterior cortical atrophy.