Pooled results revealed that DFS was shorter in cancer patients with elevated TBL1XR1 protein (HR: 1.51, 95 % CI: 1.19–1.84, p < 0.001) (Figure 3), without significant heterogeneity among studies (I2=21.5 %, Ph=0.281). The gene discussed is TBL1XR1; the disease is cancer.