Notably, mutual exclusivity analysis using 500 clinical breast cancer samples from the TCGA database indicated a high likelihood of co-occurrence of alterations in the TP53, MYC, WRN, NDRG1, NOTCH3, UBR5, and BRD4 genes, all of which are involved in the above-mentioned interaction network. This evidence concerns the gene UBR5 and breast carcinoma.