MALAT1 and colonic neoplasm: Thus, we selected miR-320a for further study, which was based on 1) it is a well-known cell-cycle miRNA, expression of which was shown to be frequently downregulated in multiple cancers and our laboratory has previously reported that miR-320 functions as proliferation suppressor gene in colon cancer [23] and 2) miR-320a could bind to MALAT1 according to RNAhybrid 2.234 (https://bibiserv.cebitec.uni-bielefeld.de/rnahybrid/) analysis.