CEACAM5 and neoplasm: In addition, multivariate analysis was performed after adjusting for age (<60 vs. ≥60), sex, s-CEA (normal vs. high), differentiation (well-differentiated, moderately differentiated vs. poorly differentiated, signet ring cell type, mucinous type), tumor location (colon vs. rectum), LVI status, PNI status, and adjuvant chemotherapy.