For example, we found overexpression of MAMDC2 and ADAMTS12 as well as underexpression of KIF1B and GPR160. Interestingly, discrete groups of tumor cells were also characterized by extremely high expression of CD248 (endosialin), which was previously described to be expressed in cells of mesenchymal origin (e.g., vascular smooth muscle cells, myofibroblasts, etc.)and by tumor cells themselves [26]. The gene discussed is ADAMTS12; the disease is neoplasm.