IGFBP6 and cancer: In contrast to the ∼5-fold increased IGFBP6 expression in DCs, there was no significant increase after hyperthermia in human aortic endothelial cells (HAEC), human renal cells (HK2), or a number of human cancer cell lines (Figure 2B and 2C, Supplementary Figure S2 in Supplementary Materials) [32,33].