In Santa Catarina, between the years 2004 and 2006, the following incidences were reported: PKU - 1:28,862, CH - 1:2,876, CF - 1:5,121, Hb - 1:14,446, and for CAH - 1:11,655 of LB.8 The gene discussed is GSTM1; the disease is congenital adrenal hyperplasia.