Currently, these criteria are based on clinical manifestations and complementary tests: a positive result for immediate skin hypersensitivity to A. fumigatus, increased total serum IgE and A. fumigatus-specific IgE and/or IgG, blood eosinophilia, oropharyngeal swab or sputum culture for the detection of A. fumigatus.11 Here, IGHE is linked to Increased total eosinophil count.