GH1 and growth hormone-producing pituitary gland neoplasm: Since GH hypersecretion should be investigated in all patients with pituitary incidentaloma, even in the absence of a phenotype (3,4,39), the conclusion of the present study may also have implications for the diagnosis of clinically silent somatotropinoma, remembering that this diagnosis could change expectant management (in the case of non-functional incidentaloma) to surgery or medicamentous treatment (in the case of somatotropinoma) (39).