The presence of thrombophilia was investigated in 12 patients, of whom four (13.8%) presented at least one thrombophilia: three had protein S clotting disorder (free antigen), one presented mutation in Factor V Leiden, and another one had immunoglobulin G anticardiolipin (IgG) and immunoglobulin M (IgM). Here, PROS1 is linked to Rare hereditary thrombophilia.