FASLG and neoplasm: ABT-510-dependent apoptosis of tumor endothelial cells was shown to be induced by their upregulation of Fas ligand, and was amplified by low doses of chemotherapeutic agents since the latter increased endothelial cells presentation of CD95 death receptor, an effect seen with docetaxel (DTX) above 1 nM (Yap et al., 2005).