Being an essential part of N‐glycosylation, the observed DPAGT1 mutations are linked to myasthenia and myopathy [Selcen 2014] and limb‐girdle congenital myasthenic syndrome with tubular aggregates.22 In addition, DPAGT1 is involved in disturbing intercellular adhesion in oral cancer.23 To measure prediction accuracy at pathogenic variants and VUS, we analyzed the following five metrics for variant‐affected residues: (1) The standard deviation of predicted relative (RelAcc) and absolute solvent accessibility. Here, DPAGT1 is linked to lip and oral cavity carcinoma.