A study in Turkish population involving 112 asthmatic patients and 180 normal controls have shown that individuals with PARP-1 762Val/Val allele were at five times higher risk of developing asthma while those with PARP-1 762Ala/Ala genotype conferred a 3.4-fold reduction in this risk, and individuals having 762Val/Ala genotype (heterozygous) conferred an even greater level of protection (149). Here, PARP1 is linked to asthma.