In particular, the images report some fields akin to Drosophila supercompetition16, with c-MYC-expressing tumour parenchyma surrounded by a crowd of stromal cells positive to Cas3 staining (Supplementary Fig. S5A,B, arrowheads indicate some stromal cells), and/or cell-cell intercalation49, with groups of tumour cells of variable dimensions entrapping clusters of stromal cells (Supplementary Figure S5C-F, arrowheads i.s.). Here, EFS is linked to neoplasm.