A novel synthetic compound that mimics the neuroprotective properties of FGF2 (SUN11602) perfected memory and learning deficits in the hippocampal-lesioned rats through prevention of neuronal death and/or promotion of neurite outgrowth, confirming the utility of such agents for treating neurodegenerative diseases such as Alzheimer’s disease [253]. This evidence concerns the gene FGF2 and early-onset autosomal dominant Alzheimer disease.