CXCL8 and amyloidosis: In addition, the co-presence of CXCL4 and CXCL8, in turn, attenuates the CXCL8-mediated rise in intracellular calcium in the amyloid progenitor cell line and enhances CXCL8-induced migration of bone-marrow-derived pro-B-cells (Baf/3) [39,40].