Basal-like and claudin-low subtypes belong to the group of triple-negative breast cancer (TNBC), which are characterized by the lack of progesterone receptor (PR), ER and HER2 expression, and have high incidence of distant disease recurrence within three years of diagnosis, with a high frequency of visceral metastases [2]. The gene discussed is PGR; the disease is triple-negative breast carcinoma.