134 genes were found to interact with lindane, and its major enriched pathways are bladder cancer (KEGG:05219), pathways in cancer (KEGG:05200), steroid hormone biosynthesis (KEGG:00140), the ErbB signaling pathway (KEGG:04012), and prostate cancer (KEGG:05215). This evidence concerns the gene EGFR and urinary bladder cancer.