There was no difference in resting [Ca2+]c in EGFP, EGFP-SOD1 WT and EGFP-SOD1 G93A-expressing neurons, suggesting that the axonal transport defect in ALS mutant SOD1 expressing neurons is not driven by changes in [Ca2+]c (Fig. 2; Supplementary Material, Fig. S2). The gene discussed is SOD1; the disease is amyotrophic lateral sclerosis.