Generation of an iPSC line carrying a distinct mutation of the nuclear lamin A/C gene derived from patients with atypical Werner syndrome and Hutchinson Gilford progeria syndrome (HGPS) was among the first approaches to mimicking premature aging phenotypes in iPSC‐derived cell types (Ho et al., 2011). The gene discussed is LMNA; the disease is Hutchinson-Gilford progeria syndrome.