LMNA and progeroid syndrome: Another possible way the regulation of these longevity‐driving processes could deteriorate over time is the loss of nucleocytoplasmic compartmentalization, as seen in progeria (Mertens et al., 2015; Soria‐Valles & López‐Otín, 2016), and also in healthy aged individuals, whose cells show evidence of increased nuclear membrane blebbing and progerin buildup (Mertens et al., 2015).