In conclusion, our data demonstrate that the dopamine D2 receptor partial agonist 2-bromoterguride does not only inhibit amphetamine-induced locomotion (AIL) and conditioned avoidance response (CAR) in rats without inducing catalepsy or causing weight gain (Franke et al. 2016); it also elicits a positive impact on cognitive impairments and social aversion in rats. This evidence concerns the gene DRD2 and Cognitive impairment.