We then used combined i.p. injections of Poly(I:C) with TLR7, TLR9, and TLR4 agonists (Imiquimod, CpG-C, and LPS, respectively), knowing that these TLR receptors are abnormally expressed in the thymus of MG patients (18, 24–26). Here, TLR4 is linked to myasthenia gravis.