Tregs express the EGFR under inflammatory conditions, as witnessed by elevated levels of EGFR found on tumor-infiltrating Tregs derived from wild type (wt) mice with B16 melanomas, as well as EGFR expression on human Tregs with an activated phenotype of FoxP3hi and CD45RA- (Zaiss et al., 2013). This evidence concerns the gene EGFR and neoplasm.