BRCA1 and breast cancer: Mammography has been considered as an appropriate screening method for breast cancer detection for many years [130] but it can’t distinguish between the solid and cystic masses and can miss up to 10–15% of the cases however MRI provides more accurate results and clear benefit to the women who are developing breast cancer due to the BRCA1 and BRAC2 genetic mutation and are present with the axillary lymph adenopathy [131].