It is estimated that approximately 10–25% of Parkinson’s disease patients have a GBA1 mutation (Parkinson-GBA1), with the most common mutations being L444P and N370S (Sidransky et al., 2009; Bultron et al., 2010; McNeill et al., 2012a, b; Schapira, 2015). Here, GBA1 is linked to Parkinson disease.