Further, many studies show that lncRNA UCA1 induces drug resistance in various cancers such as bladder cancer, ovarian cancer, breast cancer, lung cancer, gastric cancer, colorectal cancer, prostate cancer and CML [21, 24, 30, 34, 38, 61, 62, 70, 71, 74, 76, 77, 87, 90, 91], thereby greatly reducing the efficacy of cancer therapy. This evidence concerns the gene UCA1 and Familial prostate cancer.