The miRNAs such as miR-204, miR-18a, miR-27b and miR-16 have demonstrated the therapeutic potential to restore drug sensitivity, whereas miRNAs such as miR-196a and proteins such as mTOR, MDR1, P27, BCL2, SRPK1, Sirt1, β-Catenin and Wnt are targets for cancer therapy. Here, ABCB1 is linked to cancer.