Moreover, lncRNA UCA1 is reactivated in various malignant tumors including bladder cancer, breast cancer, cervical cancer, colorectal cancer, esophageal squamous cell carcinoma, hepatocellular carcinoma, gastric cancer, lung cancer, melanoma, ovarian cancer, thyroid cancer, tongue squamous cell carcinoma, prostate cancer, acute myeloid leukemia, pancreatic cancer, glioma and osteosarcoma [19, 21–33]. The gene discussed is UCA1; the disease is esophageal squamous cell carcinoma.