The majority of those cases were of cortical location (around 75%), had better overall outcome (5-year OS > 90% for LGG-like and ∼ 60% for PXA-like cases) and frequently harbored BRAF-V600E mutations (48% in PXA-like and 31% in LGG-like). This evidence concerns the gene BRAF and pleomorphic xanthoastrocytoma.