Univariate Cox regression analysis showed that GS≥7 (HR, 0.319, CI=0.166-0.614,P=0.0006), Tumor state (pT3/4 tumors) (HR, 0.580, CI=0.391-0.861,P=0.0068), NR6A1 expression (HR, 0.612, CI=0.411-0.912,P=0.0159) and preoperative PSA(HR, 1.015, CI=1.007-1.023, P=0.0004) were all associated with a significantly shorter biochemical recurrence-free survival (Table 3). The gene discussed is NR6A1; the disease is neoplasm.