In IHC reaction with SP142 antibody, percentages of SCC patients with PD-L1 expression on ≥5% and ≥50% of tumor cells (71.4% and 42.9%, respectively) were significantly higher (p<0.01 and p<0.05, respectively) compared to those of non-SCC patients (26.5% and 14.7%, respectively) (Table 3 and 4). This evidence concerns the gene CD274 and neoplasm.