Similarly, compared to active BD patients, the methylation level of CG-2.3.4.5 and CG-10.11 units in TGF-β was also significantly reduced in CD4+T cells from inactive BD patients (P=5.63×10−5, P=1.88×10−4, Figure 4B and 4C). Here, TGFB1 is linked to Behcet disease.