PTN expression correlated significantly with the necrosis rate (p=0.003) and local tumor recurrence (p=0.001), but not with other clinical features including gender (p=0.924), age (p=0.274), tumor location (p=0.472), lung metastasis (p=0.109) and TNM stage (p=0.135). The gene discussed is PTN; the disease is neoplasm.