VIM and hepatocellular carcinoma: pHCC intrahepatic xenografted tumors were also histomorphologically characterized by classical histological features of human HCC, including arrangement of neoplastic cells in more than 3 cell layer thick expanded liver cell plates with regional pseudoacinar and sheet formations supported by a thick wall of vascularized stroma (Figure 3A), as well as expression of cytokeratin (Figure 3B) and vimentin (Figure 3C) consistent with the EMT observed in human HCC.