In addition, data from The Cancer Genome Atlas (TCGA) database (http://cancergenome.nih.gov), including 223 CRC tumors, confirmed a negative correlation between DCR1 DNA methylation and DCR1 mRNA expression (Pearson correlation of −0.4, p=3.4E-9; Figure 4C). Here, TNFRSF10C is linked to colorectal carcinoma.