As shown in Figure 2A, the YKL-40 mRNA expression levels were up-regulated and significantly greater in both DM2-CHD and CHD subjects compared with controls, moreover, the levels of YKL-40 mRNA expression were significantly higher in DM2-CHD patients than that in CHD subjects (1.716±0.083 vs. 1.47±0.132; p<0.05). Here, CHI3L1 is linked to coronary artery disorder.